Korean J Med.  2000 Oct;59(4):447-451.

A case of bilateral primary adrenal lymphoma

• Park KK
• Jang YS
• Lee HS
• Song HS
• Park SK

Abstract

Primary adrenal lymphoma is extremely rare with only 65 cases reported in the worldwide literature until 1998. The presenting symptom may be related to the lymphoma itself or to adrenal insufficiency. Most of the lymphomas were of B cell diffuse large cell type with only two seemed to be T-cell in origin. The therapeutic modalities include surgery, combination chemotherapy, surgery followed by chemotherapy and/or radiation therapy, in addition to corticosteroid replacement. A 65 year old man with chronic hepatitis C and hemangioma of liver presented with general weakness. Abdominal ultrasonography showed bilateral adrenal masses. The adrenal masses were diagnosed as a primary adrenal non-Hodgkin's lymphoma by open biopsy. The histologic findings were consistent with B cell diffuse large cell lymphoma. After three cycles of CHOP chemotherapy, the adrenal mass disappeared on follow up abdominal CT scan, but the patient died 4 months after diagnosis due to sepsis.

Keyword

Adrenal glands; Lymphoma; Non - Hodgkin

MeSH Terms

Adrenal Glands
Adrenal Insufficiency
Aged
Biopsy
Diagnosis
Drug Therapy
Drug Therapy, Combination
Follow-Up Studies
Hemangioma
Hepatitis C, Chronic
Humans
Liver
Lymphoma*
Lymphoma, Large B-Cell, Diffuse
Lymphoma, Non-Hodgkin
Sepsis
T-Lymphocytes
Tomography, X-Ray Computed
Ultrasonography