Korean J Med.
2002 Dec;63(6):682-687.
A case of membranous glomerulonephritis induced by lithium
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Hallym University, Chunchon, Korea. jwn8671@unitel.co.kr
- 2Department of Pathology, College of Medicine, Hallym University, Chunchon, Korea.
Abstract
- The lithium is widely employed as a psychotropic agent, specially in manic illness. Lithium nephrotoxicity can be divided into three main categories: nephrogenic diabetes insipidus, acute intoxication, chronic nephropathy including interstitial nephropathy and glomerulopathy manifested as nephrotic syndrome. But, nephrotic syndrome induced by lithium is very rare. We reported a nephrotic syndrome induced by lithium in a 27-year-old woman who was taking lithium carbonate for 11 years due to bipolar disorder. Renal biopsy showed membranous nephropathy. After withdrawal of lithium, clinical symptoms and proteinuria significantly improved.
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