Korean J Med.
2008 Apr;74(4):435-440.
A case of primary malignant uterine cervical Non-Hodgkin's lymphoma with breast involvement
- Affiliations
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- 1Department of Internal Medicine, Eulji University School of Medicine, Daejon, Korea. lee982023@eulji.ac.kr
- 2Department of Radiology, Eulji University School of Medicine, Daejon, Korea.
- 3Department of Anatomic Pathology, Eulji University School of Medicine, Daejon, Korea.
- 4Department of Clinical Pathology, Eulji University School of Medicine, Daejon, Korea.
Abstract
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Primary lymphoma arising from the uterine cervix has been rarely encountered, and breast involvement is rare because of the relative paucity of lymphoid tissue in the breast. A 32-year-old woman with a primary malignant lymphoma of the uterine cervix and breast involvement is reported. The patient presented with post-coital vaginal bleeding, and punch biopsy of the cervix revealed the diffuse large B cell type of malignant lymphoma. PET-scan was done for staging, and abnormal FDP uptakes were detected in a uterine cervical mass and breast nodule. Ultrasonography-guided needle biopsy was done for the breast mass, and 2 biopsied nodules revealed fibroadenoma and diffuse large B cell lymphoma. The patient (Ann Arbor stage IV) was treated with 6 cycles of combination chemotherapy with CHOP plus rituximab. The patient went into complete remission. Thereafter, 4500cGy pelvic irradiation was done for adjuvant therapy.