Korean J Health Promot.  2011 Jun;11(2):57-63.

The Association between Metabolic Syndrome and Intraocular Pressure

• Lee GH

Abstract

BACKGROUND
Many studies have reported that high intraocular pressure (IOP), a well-known risk factor for glaucoma and especially primary open angle glaucoma, is associated with age, sex, hypertension, diabetes mellitus and obesity. We investigated the association between IOP and metabolic syndrome (MS).
METHODS
We measured IOP and MS components according to the National Cholesterol Education Program Adult Treatment Panel III and the American Heart Association and the National Heart, Lung, and Blood Institute with modified guideline for waist circumference. High IOP was defined as > or =21 mmHg in one or both eyes.
RESULTS
Looking at the components of MS in men, those with high blood pressure (BP) had significantly higher IOP. In regression analysis, fasting glucose, triglyceride, systolic BP and diastolic BP were positively, and age was negatively associated with IOP. In women, those with high fasting glucose and BP had significantly higher IOP. In regression analysis, diastolic BP, systolic BP, fasting glucose, body mass index and triglyceride were positively associated with left IOP while diastolic BP, fasting glucose and triglyceride were positively associated with right IOP. There were significantly increasing odds ratios for high IOP according to the number of components of MS.
CONCLUSIONS
These findings suggest that MS and its components are significantly associated with IOP.

Keyword

Intraocular pressure; Metabolic syndrome; Blood glucose; Blood pressure; Triglyceride

MeSH Terms

Adult
American Heart Association
Blood Glucose
Blood Pressure
Body Mass Index
Cholesterol
Diabetes Mellitus
Fasting
Female
Glaucoma
Glaucoma, Open-Angle
Glucose
Humans
Hypertension
Intraocular Pressure
Male
National Heart, Lung, and Blood Institute (U.S.)
Obesity
Odds Ratio
Risk Factors
Waist Circumference
Blood Glucose
Cholesterol
Glucose