Korean J Health Promot.  2013 Sep;13(3):87-92.

The Association Between Colon Polyp and the Metabolic Syndrome in Asymptomatic Korean Adults

• Park HY
• Kim JR
• Seo JY
• Shin KS
• Yoo BW
• Cho YJ
• Oh JE

Abstract

BACKGROUND
Recently, the prevalence of colorectal cancer related with metabolic syndrome is increasing in Korea. The aim of this study was to reveal a relationship between components of metabolic syndrome and the development of colon polyp.
METHODS
Among the subjects who visited a health promotion center of one university hospital and underwent colonoscopic examination from February 2010 to February 2011, a total of 1,630 (males 1,156, females 474) asymptomatic adults were included for the study. Sex, age, body mass index, waist circumference, blood pressure, fasting blood glucose, total cholesterol, triglyceride, HDL-cholesterol levels and the presence of colorectal polyps were measured. Alcohol consumption, smoking and exercise were assessed by a self-administered questionnaire. Metabolic syndrome was defined by criteria of 2004 American Heart Association/Updated NCEP Adult Treatment Panel III.
RESULTS
The prevalence of colon polyps and metabolic syndrome was 21.7% and 16.0% respectively among study subjects. After adjustment for sex and age, metabolic syndrome (odds ratio [OR]=1.72, 95% confidence interval [CI] 1.05-2.82, P=0.031) and waist circumference (OR=1.04, 95% CI 1.01-1.06, P=0.009) were associated with increased risk of colorectal polyps.
CONCLUSION
Metabolic syndrome and waist circumference were associated with increased risk of colon polyps in asymptomatic Korean adults.

Keyword

Colon polyp; Metabolic syndrome; Waist circumference

MeSH Terms

Adult*
Alcohol Drinking
Blood Glucose
Blood Pressure
Body Mass Index
Cholesterol
Colon*
Colorectal Neoplasms
Fasting
Female
Health Promotion
Heart
Humans
Korea
Polyps*
Prevalence
Smoke
Smoking
Triglycerides
Waist Circumference
Surveys and Questionnaires
Blood Glucose
Cholesterol
Smoke