Korean J Gastroenterol.
1998 Dec;32(6):757-772.
A Clinical Study on the Prognosis of Hepatocellular Carcinomain Relation to Therapeutic Modalities
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
- 2Department of Radiology, College of Medicine, Korea University, Seoul, Korea.
- 3Department of Surgery, College of Medicine, Korea University, Seoul, Korea.
- 4Department of Statistics, Korea University, Seoul, Korea.
- 5Department of Statistics, Eulji Medical College, Daejun, Korea.
Abstract
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BACKGROUND/AIMS: Recent progress in both diagnostic and therapeutic technique of hepatocellular carcinoma (HCC) appears to improve the prognosis. The purpose of this study was to evaluate the prognosis of HCC in relation to treament methods.
METHODS
A new staging scheme (PI stage) based on the prognostic index was used. A total of 487 patients with HCC were divided into 4 treatmen groups; no treatment (No Tx), transarterial oily chemoembolization (TOCE), combination of percuta neous ethanol injection and TOCE (CEI), partial hepatectomy (OP).
RESULTS
In PI stage I, the groups of CEI and OP showed similar survival rates, and both prolonged survival compared with the group of TOCE. In PI stage II, CEI gave a better survival than TOCE, whereas OP could not improve survival rate, compared with TOCE. In PI stage III, only TOCE was done in some patients and i prolonged survival, particularly when serum bilirubin was 1.5 mg/dL or less.
CONCLUSIONS
In the P stage I, operation is recommended firstly, but if operation is impossible, CEI could be selected. CE may be chosen as the first treatment choice in PI stage II. In PI stage III, TOCE may be considered for patients whose serum bilirubin is 1.5 mg/dL or less.
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