Korean J Gastroenterol.  1999 Jul;34(1):116-119.

Cystic Leiomyosarcoma with Unusual Manifestations

Abstract

Cystic leiomyosarcoma is generally developed by significant necrosis or hemorrhage due to rapid growth within a short period of time. However, we experienced a case of cystic leiomyosarcoma that apparently arised from a benign cystic lesion of the duodenum, and progressed in a very unusual clinical course. The tumor was first identified as a thin-walled cyst, which was initially thought to be a duplication cyst. During clinical follow-up over four years, the wall of the cystic mass became irregularly thickened, duodenal mucosa was eroded, and folds converged. These findings suggested the possibility of malignant transformation. Grossly, the resected mass was mostly necrotic and was consisted of bundles of spindle cells, which was consistent with the features of leiomyosarcoma of grade 2.

Keyword

Gastrointestinal tract; neoplasm; Leiomyosarcoma

MeSH Terms

Cytochrome P-450 CYP1A1
Duodenum
Follow-Up Studies
Gastrointestinal Tract
Hemorrhage
Leiomyosarcoma*
Mucous Membrane
Necrosis
Cytochrome P-450 CYP1A1
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