Korean J Fam Med.  2011 Mar;32(3):173-181. 10.4082/kjfm.2011.32.3.173.

Gender Difference in the Level of HDL Cholesterol in Korean Adults

Affiliations
  • 1Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Family Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea. drparkhyunah@gmail.com
  • 3Department of Health Management, Inje Institute of Advanced Studies, Seoul, Korea.
  • 4Department of Laboratory Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
  • 5Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, USA.

Abstract

BACKGROUND
High density lipoprotein (HDL) cholesterol level varies with ethnicity and gender. In Korea there has not been an agreement on standards for HDL cholesterol level. Therefore, in order to establish a foundation for research on HDL cholesterol, we investigated the gender difference in HDL cholesterol level after adjusting associated factors.
METHODS
The study population included 4,465 individuals (1,833 men, 2,632 women) representing 33,502,918 Koreans 20 years of age or older, who participated in the 2005 Korean National Health and Nutrition Survey. After stratifying by gender, we analyzed the HDL cholesterol level according to the general characteristics of the study population. Then we identified independent factors associated with HDL cholesterol level. After adjusting for covariates, we estimated the gender difference in HDL cholesterol level.
RESULTS
We demonstrated that age, current smoking, body mass index, alcohol intake, triglyceride and low density lipoprotein cholesterol level have significant impact on HDL cholesterol level. In addition, educational status was also an important factor for men, while fat intake was a significant factor for women. After adjusting associated factors, the means (standard errors) of HDL cholesterol level were 43.8 (0.2) mg/dL in men and 46.3 (0.2) mg/dL in women, respectively.
CONCLUSION
The mean gender difference in HDL level (2.5 mg/dL) in Korean adults was, therefore, less than those observed in previous western studies.

Keyword

Cholesterol; High Density Lipoprotein; Gender Difference; Korean National Health and Nutrition Survey (KNHANES)

MeSH Terms

Adult
Body Mass Index
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
Educational Status
Female
Humans
Korea
Lipoproteins
Male
Nutrition Surveys
Smoke
Smoking
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
Lipoproteins
Smoke
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