Korean J Fam Med.  2012 Mar;33(2):70-78. 10.4082/kjfm.2012.33.2.70.

The Relationship between Metabolic Syndrome and Pulmonary Function

Affiliations
  • 1Department of Family Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea. cinta@eulji.ac.kr

Abstract

BACKGROUND
Impaired lung function is associated with mortality rate from cardiovascular and all other death causes. There were previous studies on the relationship between lung function impairment and metabolic syndrome, but they are insufficient. This study was conducted on Koreans to analyze each component of metabolic syndrome as well as its variability between sexes.
METHODS
1,370 subjects underwent a health examination at the Eulji General Hospital Health Center. We examined the association between lung function measurement (forced expiratory volume for 1 second [FEV1], forced vital capacity [FVC], FEV1/FVC) and metabolic syndrome using Student t-test, Pearson partial correlation coefficient, and analysis of covariance for statistical analysis, and we adopted metabolic syndrome defined by American Heart Association/National Heart, Lung, and Blood Institute in Asia.
RESULTS
Men with metabolic syndrome tended to experience lung function impairment. In terms of association to each metabolic syndrome component, metabolic syndrome components in men were associated with pulmonary function impairment and the more metabolic syndrome diagnostic criteria factors the patients had, the more severe their pulmonary function tended to decline. In women, waist circumference, triglyceride and high-density lipoprotein cholesterol were associated with pulmonary function change.
CONCLUSION
In men, all metabolic syndrome components were associated with pulmonary function impairment, and the more metabolic syndrome components men had, the more severe their pulmonary functions decline. In women, components of metabolic syndrome were not associated with pulmonary function impairment.

Keyword

Metabolic Syndrome; Forced Expiratory Volume; Forced Vital Capacity; Obesity, Abdominal

MeSH Terms

Cause of Death
Cholesterol
Female
Forced Expiratory Volume
Heart
Hospitals, General
Humans
Lipoproteins
Lung
Male
Obesity, Abdominal
Vital Capacity
Waist Circumference
Cholesterol
Lipoproteins
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