Korean J Dermatol.  1997 Feb;35(1):144-149.

A Case of Type IIa Hyperlipoproteinemia with Xanthoma Planum , Xanthoma Tendinosum and Xanthoma Tuberosum

• Park JI
• Hur KH
• Kim HO
• Park SR

Abstract

We report a case of a 59 year-old female with hyperlipoproteinernia who had xanthoma tuberosum, xanthoma tendinosurn and xanthoma planum. Yellowish nodules appeared on the right elbow 26 years ago and the lesions gradually increased in size and spread to the elbow, hand, knee, foot and achilles tendon. Except for the skin lesion, she was normal on physical examination. The laboratory findings showed that the serum cholesterol, beta lipoprotein and total lipid were increased. The beta band was rnarkedly elevated on electrophoresis, which suggested type IIa hyperlipoproteinemia. Histopathological findings shc wed many aggregates of foam cells and foreign body giant cells were seen in the dermis.

Keyword

Beta lipoprotein; Type Iia hyperlipoproteinemia; Xanthoma

MeSH Terms

Achilles Tendon
Cholesterol
Dermis
Elbow
Electrophoresis
Female
Foam Cells
Foot
Giant Cells, Foreign-Body
Hand
Humans
Hyperlipoproteinemia Type II*
Knee
Lipoproteins
Middle Aged
Physical Examination
Skin
Temazepam*
Xanthomatosis*
Cholesterol
Lipoproteins
Temazepam