Korean J Dermatol.
1997 Jun;35(3):418-423.
Clinical Study of ZalsmingR on Xerosis and Pruritus
Abstract
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BACKGROUND: Xerosis is a relatively common disorder, especially in the elderly. The condition is characterized by fine scaling and is associated with generalized pruritus.
OBJECTIVE
The purpose of this study was to evaluate the clinical efficacy, safety and tolerability of Zalsming cream in patients with xerosis and pruritus.
METHODS
Thirty patients were treated with Zalsming cream. Clinical efficacy, as measured by the score of subjective symptom and objective signs, transepidermal water loss(TEWL) and electron microscopic finding, were asessed at 2, 4, and 6 weeks after topical application of the cream.
RESULTS
The scores of clinical signs and TEWL showed statistically significant improvements. No one developed any local or systemic side effects.
CONCLUSION
Topical application of Zalsming cream was found to be effective and safe for patients suffering from xerosis and pruritus.
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