Korean J Dermatol.
2000 Aug;38(8):1037-1044.
Comparative Clinical Study of Segmental Vitiligo and Non-Segmental Vitiligo
- Affiliations
-
- 1Department of Dermatology, College of Medicine, Dongguk University, Kyongju, Korea.
- 2Taegu Severance Skin Clinic.
- 3Dr. Woo & Hann's Skin Clinic, Seoul, Korea.
Abstract
-
BACKGROUND: Vitiligo was divided into two types, segmental and non-segmental vitiligo.
OBJECTIVE
The purpose of our study is to investigate the clinical differences of segmental and non-segmental vitiligo.
METHODS
A cross-sectional study, using standard questionnaire items on 1190 cases of vitiligo was performed.
RESULTS
The results were summarized as follows 1. The non-segmental vitiligo was 2.4fold more common than segmental vitiligo. 2. The mean age of onset was older in non-segmental vitiligo than in segmental vitiligo. 3. The mean duration was longer in non-segmental vitiligo. 4. The depigmented area was larger in non-segmental vitiligo. 5. The incidences of Koebner phenomenon, progressiveness and mucosal involvement were more common in non-segmental vitiligo. 6. There were no differences about sex ratio, blood typing, family history, and associated disorders.
CONCLUSION
Segmental and non-segmental vitiligo differ substantially in various clinical manifestations, which suggests that two types of vitiligo have different pathogenic mechanism.