Korean J Dermatol.
2003 May;41(5):663-665.
A Case of Scleroderma Probably Induced by Colon Cancer or 5-FU Therapy
- Affiliations
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- 1Department of Dermatology, Yonsei University College of Medicine, Wonju, Korea. skahn@wonju.yonsei.ac.kr
Abstract
- Scleroderma is a chronic disease of unknown etiology, it is the sclerosis of the skin characterized by the appearance of circumscribed or diffuse, hard, smooth and ivory-colored areas that are immobile and give the appearance of hidebound skin. Progressed scleroderma can lead to develop various tumors by affecting organs. It is rarely reported that the tumor itself or systemic chemotherapy could be one of the causes of scleroderma. Up to now, the pathogenesis about scleroderma occurring from cancer itself or anticancer drugs are uncertain.
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