Korean J Dermatol.  2003 May;41(5):645-648.

A Case of Stasis Dermatitis with Secondary Lipodermatosclerosis in a Patient with Antithrombin III Deficiency

• Lee JD
• Bae EY
• You CE
• Cho SH

Abstract

Antithrombin is one of the main endogenous anticoagulants. Antithrombin deficiency may result from hereditary or acquired factors. Inherited antithrombin deficiency is an uncommon autosomal disorder associated with a tendency to venous thromboembolism. Stasis dermatitis occurs as a result of venous stasis caused by venous incompetence or deep vein thrombosis. Furthermore, lipodermatosclerosis that refers to the skin induration and hyperpigmentation of the legs, often occurs in patients who have venous insufficiency. We report a case of stasis dermatitis, complicated by lipodermatosclerosis on both legs of a patient with hereditary antithrombin III deficiency.

Keyword

Antithrombin III deficiency; Lipodermatosclerosis; Stasis dermatitis

MeSH Terms

Anticoagulants
Antithrombin III Deficiency*
Antithrombin III*
Dermatitis*
Fibrin
Humans
Hyperpigmentation
Leg
Skin
Venous Insufficiency
Venous Thromboembolism
Venous Thrombosis
Anticoagulants
Antithrombin III
Fibrin