Korean J Dermatol.
2005 Mar;43(3):394-397.
A Case of Pseudoporphyria
- Affiliations
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- 1Department of Dermatology, College of Medicine, Gyeongsang National University, Chinju, Korea. deroh@nongae.gsnu.ac.kr
- 2Gyeongsang Institute of Health Science, Gyeongsang National University, Chinju, Korea.
Abstract
- Pseudoporphyria is a generic term that is used to describe photoaggravated bullous dermatoses associated with multiple iatrogenic causes, including medications and dialysis. The bullous lesions of pseudoporphyria are similar to those of porphyria cutanea tarda, both clinically and histologically, but they occur in the absence of the abnormally high levels of porphyrins which are found in true porphyrias. Treatment entails discontinuation of suspected agents and sun protection, especially against UVA wavelengths. We report a case of pseudoporphyria in a 28-year-old male who had erythematous crusted erosions, vesicles and hyperpigmented macules on his face and both forearms. A biopsy from his Lt. forearm revealed subepidermal bullaes with festooning of dermal papillae, and mild lymphocytic perivascular infiltrations. However laboratory tests for porphyrin were negative in his urine, blood and stool.
