Korean J Dermatol.
2010 Mar;48(3):232-236.
A Case of Erythrodermic Mycosis Fungoides Treated with Gemcitabine
- Affiliations
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- 1Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. miumiu@amc.seoul.kr
- 2Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract
- Erythrodermic mycosis fungoides (MF) denotes a condition in which erythroderma occurs in patients with otherwise typical clinical features of MF. Gemcitabine is a novel treatment regiment for MF. A 16-year-old boy presented in the hospital with skin lesions that showed generalized erythema with scaling, several plaques, and nodules with ulceration on the extremities and trunk. He was diagnosed with erythrodermic MF. His lesions did not improve with methotrexate (7.5 mg/week) and PUVA for 6 months, so his treatment regimen was changed to systemic gemcitabine therapy (1,000 mg/m2 per week). After 6 cycles of gemcitabine, his skin lesions disappeared. We report a case of erythrodermic MF treated by gemcitabine.
