Korean J Blood Transfus.
2008 Dec;19(3):266-269.
Maintenance of Recurred Focal Segmental Glomerulosclerosis of Transplanted Kidney for More Than 9 Months by Performing Plasmapheresis
- Affiliations
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- 1Department of Laboratory Medicine, School of Medicine, Pusan National University, Busan, Korea. martyrs@hanmail.net
- 2Department of Internal Medicine, School of Medicine, Pusan National University, Busan, Korea.
Abstract
- Focal segmental glomerulosclerosis (FSGS) is thought to be caused by FSGS permeability factor (FSGF) in the plasma, and this plasma FSGF might be responsible for FSGS recurrence after transplantation. Therefore, to reduce the FSGF in plasma, plasmapheresis (PE) is usually used to treat recurred FSGS. We report here on the PE treatment of 33-year-old women who had recurrence of FSGS after transplantation. After recurrence, she was treated by intensive PE for 1 month and she achieved complete remission. But because the proteinuria was increased when we stopped PE, we regularly continued PE for 28 month with the patient in a state of partial remission. To the best of our knowledge, this is the second report on treating recurred FSGS with intensive PE and this is the first report for long term maintenance with performing regular PE.
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