Korean J Anesthesiol.  2001 Jan;40(1):16-21. 10.4097/kjae.2001.40.1.16.

The Effect of Preoperative Pulmonary Arterial Pressure and Right Ventricular Function on the Changes in Right Ventricular Function after Mitral Valve Replacement

• Kang SH
• Kwak YL
• Shim YH
• Oh YJ
• Nam SB
• Park JH
• Hong YW

• KMID: 2298965
• DOI: http://doi.org/10.4097/kjae.2001.40.1.16

Abstract

BACKGROUND: In patients with mitral valvular disease with pulmonary hypertension (PHT) accompanying right ventricular (RV) dysfunction, mitral valve replacement (MVR) improves RV function and other hemodynamic variables in long term follow-up. However, there are controversies in improvement of RV function in the immediate postoperative period. We compared the RV function immediately after a MVR with a pulmonary artery catheter (PAC) between patients with normal and decreased RV function with PHT preoperatively.
METHODS
Twenty nine patients undergoing a MVR were included in the study. The patients (n = 14) with mean pulmonary arterial pressure (PAP) < or = 25 mmHg were assigned to group I and the patients (n = 15) with mean PAP 25 mmHg were assigned to group II. A PAC with rapid response-thermistors which enables us to determine right ventricular ejection fraction (RVEF) was inserted in all patients and hemodynamic variables were measured before and after cardiopulmonary bypass (CPB).
RESULTS
After CPB, PAP, pulmonary vascular resistance index (PVRI), and RV end-diastolc volume (RVEDV) were significantly decreased and RVEF was significantly increased in group II compared with group I in which no hemodynamic variables were changed.
CONCLUSIONS
A MVR decreased RV afterload and increased RV function more significantly in patients with preoperative PHT accompanying RV dysfunction than in patients with normal PAP preoperatively.

Keyword

Blood pressure, hypertension: pulmonary; Heart: hemodynamics; right ventricular ejection fraction; Surgery: mitral valve replacement

MeSH Terms

Arterial Pressure*
Cardiopulmonary Bypass
Catheters
Hemodynamics
Humans
Hypertension, Pulmonary
Mitral Valve*
Postoperative Period
Pulmonary Artery
Stroke Volume
Vascular Resistance
Ventricular Function, Right*