Korean J Androl.
2006 Aug;24(2):84-88.
Double-blind, Placebo-controlled, Multi-center Study for Therapeutic Effects of Mountain Panax Ginseng C.A. Meyer Extract in Men with Erectile Dysfunction: a Preliminary Report
- Affiliations
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- 1Department of Urology, Chungnam National University Medical School, Daejeon, Korea.
- 2Department of Urology, Eulji University College of Medicine, Daejeon, Korea.
- 3Department of Urology, Chungbuk National University Medical School, Cheongju, Korea.
- 4Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, Korea.
- 5Infertility Clinic, Sanborn Jeil Women's Hospital, Gunpo, Korea.
- 6Department of Urology, Kyung Hee University, East-West Neomedical Center, Seoul, Korea. hlle61@hanmail.net
Abstract
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PURPOSE: We investigated the effect of 100-year-old mountain ginseng(Panax ginseng C.A. Meyer, PG-CAM) extract on patients with erectile dysfunction(ED).
MATERIALS AND METHODS
A total of 35 patients with ED(23 patients in PG-CAM administration group, 12 in placebo group) were enrolled in this double-blind study. The drug was administered for 12 weeks. Before and after administration, patients took the self-administered IIEF-5 questionnaire and were tested for serum hormone levels(testosterone, LH, FSH, estradiol), complete blood count, liver and renal function test, and urinalysis.
RESULTS
The IIEF-5 scores for the placebo group were 19.7+/-2.3 and 19.9+/-3.6 before and after treatment, respectively. For all patients taking PG-CAM, IIEF-5 scores increased 18.1+/-5.6 to 20.2+/-4.5. For those patients with initial scores below 17, IIEF-5 scores increased from 12.4+/-6.2 to 19.7+/-6.7. These results indicate that PG-CAM may increase erectile function in ED patients, particularly those with poor erection. No changes were detected in hormonal levels or blood tests. No toxic side effect were reported.
CONCLUSIONS
IIEF-5 score improved significantly in ED patients treated with PG-CAM, suggesting that PG-CAM extract could be a treatment candidates for ED.
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