J Rhinol.  2013 May;20(1):26-30.

Clinical Experience of Sinonasal Schwannomas

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, South Korea. lhman@korea.ac.kr
  • 2Department of Biomedical Sciences, Korea University College of Medicine, Seoul, South Korea.
  • 3Institute for Medical Devices Clinical Trial Center, Korea University College of Medicine, Seoul, South Korea.
  • 4Department of Otorhinolaryngology-Head and Neck Surgery, Yeungnam University College of Medicine, Daegu, Korea.

Abstract

BACKGROUND
Schwannomas are benign tumors of ectodermal origin derived from Schwann cells of the nerve sheath. Approximately less than 4% of these tumors are found in the paranasal sinuses and there has been little information reported concerning the presentation and surgical management of sinonasal schwannomas. The purpose of this study was to analyze the clinical data, management, and long-term outcomes of sinonasal schwannomas.
METHODS
Retrospective chart review of patients with sinonasal schwannomas treated from January 2001 to March 2012 was performed. Clinical data and follow-up information were obtained from a review of the patients' charts and the operative, anesthesia, and pathology reports.
RESULTS
There were 4 females and 4 males included in this study. The mean age was 37.5 years (range, 22-51 years). The mean tumor size was 3.1 cm (range 1.0-6.0 cm). The origin of the tumors included: nasal septum (n = 2), nasal vestibule (n = 2), pterygopalatine fossa (n = 2), ethmoid sinus (n = 1), and inferior turbinate (n = 1). Seven patients had endoscopic resections and one patient with a schwannoma in the nasal vestibule underwent a sublabial approach. The mean follow-up was 59 months. There were no tumor recurrences during the study period.
CONCLUSIONS
Schwannomas in sinonasal cavity can be treated effectively with the endoscopic approach with minimal morbidity and long-term disease control.

Keyword

Schwannoma; Sinonasal; Endoscopic Surgery; Nasal Tumor

MeSH Terms

Anesthesia
Ectoderm
Ethmoid Sinus
Female
Follow-Up Studies
Humans
Male
Nasal Septum
Neurilemmoma*
Paranasal Sinuses
Pathology
Pterygopalatine Fossa
Recurrence
Retrospective Studies
Schwann Cells
Turbinates
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