The effects of Cigarrete Smoking on Serum Lipid Profile in young-and middle-aged men

Suh, Young Sung

Abstract

BACKGROUND: Cigarette smoking is a major risk factor for cardiovascular disease and a correctable risk factor. In middle and old-aged men, cardiovascular disease is in prevalence than at any other age. Most smokes, start smoking in their twenties and continued to do so until middle to-old-age. Cardiovascular disease are higher prevalence than any other of that in middle and old aged men, especia]Iy in young-and middle-aged men. We examined the association between smoking and their level of plasma lipids.
METHODS
Subjects were 238 healthy male non-smokers and 238 male smoker of 21-45 years of age, age matched, and were comparatively observed from May 1 to November 30, 1997 in a university hospital, Taegu, Korea. Subjects were interviewed by a research doctor who recorded subject's sociodemographic data, drinking amount, exercise, smoking status and smoking amount. We checked the level of serum total cholesterol, HDL-cholesterol, tri-glyceridea on a fasting state and BMI.
RESULTS
The results showed that smoking had a remarkable influence on HDL cholerol, triglyceride, atherogenic index(ratio of total cholesterol to HDL cholesterol) between nonsmoker and healthy male smokers. After adjusting for body mass index, the level of HDL cholesterol of smoking group in 31-35 year age group were obviously lower than nonsmoking that age group. The level of triglycerlde in 31-35, 41-45 year age group were obviously higher than same nonsmoking groups. Atherogenic index in 31-35 year age group was obviously higher than nonsmoking that age group. But, no association between cigarette smoking and level of plasma total cholesterol was observed. HDL cholesterol, glyceride, atherogenic index were significant difference beyond 11 pack-years or 20 cigarettes/day smoking groups than nonsmoking groups.
CONCLUSIONS
Based on the these finding, it is recommend that smoking cessation strategies for perceived healthy third decade and fourth decade men build up. I suggest smoking cessation education should start in the early age as soon as possible.