Korean J Urol.  2006 Jan;47(1):101-104. 10.4111/kju.2006.47.1.101.

Bladder Transitional Cell Carcinoma Masquerading as Tuberculous Contracted Bladder

• Liu CS
• Seo SH
• Jang YH
• Park YW
• Lee JH
• Min SK

• KMID: 2294224
• DOI: http://doi.org/10.4111/kju.2006.47.1.101

Abstract

Bladder cancer is generally manifested with gross hematuria and this is the most common urinary tract neoplasm in Korea, but it is very rare to find it combined with a contracted bladder. A case of contracted bladder was suspected as being recurred urinary tuberculosis; because of her past history, the urine analysis and cystoscopic findings seemed to resemble the chronic inflammation associated with urinary tuberculosis, and the transurethral biopsy reported only chronic inflammation. Yet the final histopathologic report after cystectomy and urinary diversion revealed that there was no tuberculosis, but rather, there was bladder transitional cell carcinoma (TCC). Therefore, any contracted bladder found in an older age patient is considered to be a urinary TCC until proven otherwise. To the best of our knowledge, this is the first case of bladder TCC combined with contracted bladder.

Keyword

Carcinoma; transitional cell; Bladder; Tuberculosis

MeSH Terms

Biopsy
Carcinoma, Transitional Cell*
Cystectomy
Hematuria
Humans
Inflammation
Korea
Tuberculosis
Urinary Bladder Neoplasms
Urinary Bladder*
Urinary Diversion
Urologic Neoplasms

Figure

• 

  Fig. 1. Cystogram via intravenous urography (IVU) shows a markedly decreased bladder volume.

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  Fig. 2. Microscopic finding of the bladder mucosa. There are some urotheliums that look like epithelial hyperplasia with atypism, but no typical tumor cells are noted (H&E, x100).

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  Fig. 3. Compared with previous IVU, this study shows a more contracted bladder and that is segmental stricture of the left distal ureter.

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  Fig. 4. Microscopic finding of the cystectomized bladder. (A) There is focal invasion of tumor cells, which show loss of maturity and polarity (H&E, x200). (B) The whole thickness of the epithelium is replaced with tumor cells, including large, pleomorphic and hyperchromatic nucleus (H&E, x100).

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