Korean J Urol.  2001 Mar;42(3):279-284.

Clinical Studies of Xanthogranulomatous Pyelonephritis

Affiliations
  • 1Department of Urology, Dong-A University School of Medicine, Busan, Korea.

Abstract

PURPOSE: Because the preoperative diagnosis of xanthogranulomatous pyelonephritis (XGP) is difficult due to its similarities to other renal diseases, the diagnosis is made postoperatively in most patients. The aim of this study was to improve preoperative diagnosis of this disease.
MATERIALS AND METHODS
We reviewed clinical characteristics, laboratory and radiological findings, preoperative diagnoses, and operative methods of 6 patients with XGP who underwent operation from March 1991 to July 1998. Mean age was 49.8 years (range 28 to 80) and male to female ratio was 1 to 2.
RESULTS
All 6 patients had flank pain and urinary tract infection. Among 6 patients, there were 3 patients (50%) with renal staghorn stone and 1 (16.7%) with ureteropelvic junction stricture. No patient was diagnosed as XGP preoperatively. Three patients (50%) diagnosed as pyonephrosis with staghorn stone preopratively underwent simple nephrectomy and 2 patients diagnosed as renal mass preoperatively underwent radical nephrectomy. One patient diagnosed as renal abscess extended to retroperitoneum and psoas muscle preoperatively was diagnosed as XGP through intraoperative frozen section biopsy of renal tissue and underwent partial nephrectomy and drainage.
CONCLUSIONS
Preoperative diagnosis of XGP will be raised through better understanding of the clinical characteristics and radiologic findings of this disease.

Keyword

Xanthogranulomatous pyelonephritis; Urinary tract infection; Staghorn stone; Ureteropelvic junction stricture

MeSH Terms

Abscess
Biopsy
Constriction, Pathologic
Diagnosis
Drainage
Female
Flank Pain
Frozen Sections
Humans
Male
Nephrectomy
Psoas Muscles
Pyelonephritis, Xanthogranulomatous*
Pyonephrosis
Urinary Tract Infections
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