Korean J Urol.  2001 Jun;42(6):627-630.

Risk Factors for Cryptorchidism

• Kim JM
• Lee NK
• Park YH

Abstract

PURPOSE: The testes normally descend into the scrotum during last trimester in ges tation. Although the cause of maldesent is not clear, abnormality of the gubernaculum testis, intrinsic testicular defect and deficient gonadotropic stimulation are considered as possible etiology. We evaluated risk factors for cryptorchidism, including low birth weight, low gestational age, twin birth and other pertinent factors.
MATERIALS AND METHODS
2,605 boys who were born in Soonchunhyang Chonan hospital between March 1997 and March 2000 were evaluated for cryptorchidism. The subjects consisted with 99 boys with cryptorchidism and 2,506 normal boys for control group. We investigated birth weight, duration of gestation, twin birth, parity, other congenital anomalies, paternal age, maternal age, previous abortion history, mode of delivery (normal vaginal delivery or Cesarean section), Apgar score (1 minute), breech presen tation and preeclampsia during pregnancy to each subject in both groups. Statistical analysis was performed using logistic regression analysis to estimate the odds ratio.
RESULTS
The birth weight less than 1,500gm and other congenital anomalies were significant risk factors for crytorchidism. The other factors showed no effect on the risk of cryptorchidism.
CONCLUSIONS
This study shows that low birth weight and other congenital anomalies are the significant risk factors for development of cryptorchidism.

Keyword

Cryptorchidism; Risk factor; Low birth weight; Congenital anomalies

MeSH Terms

Abortion, Induced
Apgar Score
Birth Weight
Chungcheongnam-do
Cryptorchidism*
Female
Gestational Age
Humans
Infant, Low Birth Weight
Infant, Newborn
Logistic Models
Male
Maternal Age
Odds Ratio
Parity
Parturition
Paternal Age
Pre-Eclampsia
Pregnancy
Pregnancy Trimester, Third
Risk Factors*
Scrotum
Testis
Twins