Adenocarcinoma of the Bladder

Lee, Sang Kon; Lee, Chongwook

Abstract

Adenocarcinoma of the bladder is rare. During the last 20 years 13 patients with adenocarcinoma of the bladder were managed at Seoul National University Hospital. The incidence is 2.2% of all primary epithelial bladder neoplams. 10 patients had primary adenocarcinoma and urachal origins were identified in 3 patients. The most common presentation was painless gross hematuria. 9 of 10 patients with primary adenocarcinoma had deeply infiltrating tumor with or without distant metastasis at the time of initial diagnosis. Various interventions including TUR and partial cystectomy were carried out. In 5 patients postoperative radiation therapy was tried without substantial improvement. Three year survival rate of primary adenocarcinoma had was averaged less than 25% regardless of the mode of treatment. One patient was free of cancer up to 3 years. 3 patients with urachal adenocarcinoma had stage D of mucin producing adenocarcinoma. Partial cystectomy including enbloc excision of urachus in 1 was carried out, partial cystectomy in 1 and exploration for unresectable tumor in one patient who died in one year.