Renal Survival after Renal Vein Ligation in Dogs

Lee, You Sik; Park, Yong Hyun

Abstract

Renal function may be adversely effected by the renal vein ligation. However, because of a rich collateral circulation, the left kidney may continue to function after renal vein ligation. This study was made to investigate the renal function recovery after the renal vein ligation in dogs. Excretory urogram and selective left renal venogram were performed before ligation, and on 1st, 2nd, 3rd and 6th week after renal vein ligation. Gross and microscopic studies were also done. The experimental results were as follows ; 1. In excretory urogram, there was non-visualization of the left kidney on 1st and 3rd week, and decreased opacity on 2nd and 6th week in complete ligation group and decreased opacity was seen on 1st week and normal appearance was found from 2nd week in the partial ligation than in the complete group. 2. In selective left renal venogram, three collateral veins were observed. The capsular and unknown vein were appeared by the 2nd week in the complete group, the capsular vein only by the 2nd week in partial group, and the ureteric vein by the 3rd week in partial ligation group only. By the 6th week capsular and ureteric vein were observed in the complete and partial group. 3. In morphologic studies, maximum increase in size of the kidney was observed by the 1st week in the complete and partial group. By the 6th week the kidney underwent an atrophic change in the complete group, but returned to normal in the partial group. 4. In conclusion, the recovery of renal function is depended on the formation of the collateral circulation which is influenced by the site and degree of renal vein ligation.