Korean J Urol.
1989 Dec;30(6):824-827.
Absorption of Prostatic Acid Phosphatase During Transurethral Prostatectomy
- Affiliations
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- 1Department of Urology, College of Medicine, Korea University, Seoul, Korea.
Abstract
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Transurethral prostatic surgery has been recognized to produce elevation of serum acid phosphatase. To evaluate the mechanism of this, we studied the prostatic acid phosphatase level of serum and irrigant solution used during transurethral prostatic resection were measured immediately postoperatively in 16 patients. The mean prostatic acid phosphatase of the irrigant solution was 66.26U/1 (S.D. 53.58) and the mean elevation of serum prostatic acid phosphatase was 12.89 U/1 (S.D. 12.08). The degree of transient elevation of serum prostatic acid phosphatase level was correlated with the elevation of irrigant prostatic acid phosphatase level and the amount of absorbed irrigant solution based on changes in serum sodium (p<0.005). Also, the elevation of serum prostatic acid phosphatase was associated with the decrease of serum sodium (p<0.05). The above results suggest that absorption of irrigant solution allows the transport of prostatic tissue substances such as prostatic acid phosphatase, and the mechanism of the elevation of serum prostatic acid phosphatase is absorption of irrigant solution containing high concentration of prostatic acid phosphatase liberated during transurethral prostatic resection.