Korean J Urogenit Tract Infect Inflamm.  2013 Apr;8(1):59-61. 10.14777/kjutii.2013.8.1.59.

Renal Actinomycosis Accompanying Staghorn Calculi

• Lee KS
• Jee JY
• Seo YE
• Jeong JS
• Cho WY

• KMID: 2289256
• DOI: http://doi.org/10.14777/kjutii.2013.8.1.59

Abstract

Actinomycosis is a chronic infectious disease that is generally caused by Actinomyces israelii. Renal actinomycosis is a very rare disease, especially accompanying staghorn calculi formation. In this article, we present a case of renal actinomycosis with the staghorn calculi formation. A 52-year-old woman presented with a 3-month history of pain in the right upper quadrant. The abdominopelvic computed tomography scan showed staghorn calculi and severe dilatation of the pelvicalyceal system of the right kidney. A right simple nephrectomy and a partial resection of the infrahepatic inferior vena cava were performed. We anticipated that the final diagnosis would be xanthogranulomatous pyelonephritis, however histopathologic tests revealed renal actinomycosis with abscess formation and extensive inflammation, glomerulosclerosis and staghorn calculi.

Keyword

Actinomycosis; Kidney calculi

MeSH Terms

Abscess
Actinomyces
Actinomycosis*
Calculi*
Communicable Diseases
Diagnosis
Dilatation
Female
Humans
Inflammation
Kidney
Kidney Calculi
Middle Aged
Nephrectomy
Pyelonephritis, Xanthogranulomatous
Rare Diseases
Vena Cava, Inferior

Figure

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  Fig. 1. Non-contrast enhanced computed tomography of the kidney showing hydronephrosis and radiopaque lesion on pelvocalyceal system of the right kidney.

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  Fig. 2. The 99mTc-dimercaptosuccinic acid scan showing the invisible right kidney that the relative function is 2% compared with 98% of the left kidney.

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  Fig. 3. (A) Gross finding, (B, C) microscopic findings (H&E stain; B, ×2; C, ×50). Grossly, the kidney is enlarged, and perirenal fat tissue is fibrotic and firmly attached with renal cortical surface. (A) On section, the kidney is mainly replaced by yellowish grey or greenish necrotic and purulent tissue, forming pseudocystic changes. In area, stony hard consistency is noted and irregular fibrotic tissue is noted, peripherally. (B) Microscopically, the kidney is nearly replaced by conglomerated abscesses, associated with chronic active inflammation with fibrosis and fine calcification. Characteristic sulfur granules rimmed by neutrophils are well observed (C) and they show central degeneration.

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