Korean J Thorac Cardiovasc Surg.  2001 Jan;34(1):97-100.

Malignant Solitary Fibrous Tumor of the Pleura: one case report

• Lee HS
• Chee HK
• Hong KW
• An HS
• Park HR
• Kim DH

Abstract

It suggested that localized fibrous tumor of the pleura originated from a primitive submesothelial mesenchymal cell. The criteria used for a judgment of malignancy were high cellularity and mitotic activity(more than four mitotic figures per 10 high-power fields), pleomorphism, hemorrhage, and necrosis. This 62 years female was admitted with dyspnea and cough. Chest X-ray and CT scan showed a huge mass in right thorax. A 23X18X12 cm, 2 Kg sized mass was excised, and it was collase the right lower lobe and right middle lobe and was adhered to the diaphragm. Pathologically, the tumor was composed high cellularity, fascicle of the spindle cells, and high mitotic numbers(27 mitosis/10HPF). Immunohistochemically, it was positive for vimentin and CD34. This tumor was diagnosised to the malignancy localized fibrous tumor. We experience a case of pleural malignant fibrous tumor and report this case with the review of literature.

Keyword

Pleural neoplasm; Fibrous neoplasm

MeSH Terms

Cough
Diagnosis
Diaphragm
Dyspnea
Female
Hemorrhage
Humans
Judgment
Necrosis
Pleura
Pleural Neoplasms
Solitary Fibrous Tumor, Pleural*
Solitary Fibrous Tumors*
Thorax
Tomography, X-Ray Computed
Vimentin
Vimentin