Korean J Psychopharmacol.
2009 Mar;20(2):90-97.
Effects of Paroxetine on Symptoms of Hwa-Byung
- Affiliations
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- 1Department of Psychaitry, Yonsei University College of Medicine, Seoul, Korea. skmin518@yuhs.ac
- 2Department of Psychiatry, College of Medicine, CHA University, Seomgnam, Korea.
- 3Department of Psychaitry, Hallym University College of Medicine, Anyang, Korea.
- 4Department of Psychiatry, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
- 5Department of Biostatistics, Yonsei University College of Medicine, Seoul, Korea.
Abstract
OBJECTIVE
This study consists of a single open clinical trial to evaluate the treatment effects of paroxetine on symptoms of hwa-byung, a Korean culture-related anger syndrome.
METHODS
Eighty-nine patients with depressive disorders, anxiety disorders, somatoform disorders, or self-labeled hwa-byung were treated with paroxetine (Paxil CR) 12.5-37.5 mg/day for 8 weeks. Treatment effects were evaluated using the Hamilton Depression Scale (HAMD), the State and Trait Anger Inventory (STAXI), and the Hwa-byung Scale.
RESULTS
Scores on all items ; total score on the Hwa-byung Scale ; scores on state anger, trait anger, and anger-in ; total score on the STAXI ; and total score on the HAM-D decreased significantly after eight weeks of paroxetine treatment compared to baseline.
CONCLUSION
Paroxetine was shown to be effective for treating symptoms of hwa-byung, a chronic anger syndrome.
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