Korean J Perinatol.  2013 Sep;24(3):180-186. 10.14734/kjp.2013.24.3.180.

Comparison of Obstetric and Neonatal Outcomes According to Oral Glucose Challenge Test in Korean Pregnant Women

• Yun SH
• Han SW
• Lee SH
• Jung YW
• Kim EH

• KMID: 2280941
• DOI: http://doi.org/10.14734/kjp.2013.24.3.180

Abstract

PURPOSE
The purpose of the study was to compare obstetric and perinatal outcomes according to glucose challenge test (GCT) in a single institution.
METHODS
One thousand six women, who were underwent antepartum gestational diabetes mellitus (GDM) screening by a GCT in mid-pregnancy and delivered at National Health Service between January 1, 2007 and July 31, 2012, were included in the study. The medical records of patients were analyzed retrospectively. The Subjects were categorized into three groups according to the results of 50 g oral GTC and 100 g oral GTC; normal glucose tolerance (NGT, n=826), less than 140 mg/dL; gestational impaired glucose tolerance (GIGT, n=128), more than 140 mg/dL but non-GDM ; gestational diabetes mellitus (GDM, n=52). Pre-existed maternal DM or hypertension and twin pregnancy were excluded. Obstetric and perinatal outcomes were compared among the three groups.
RESULTS
Maternal age, parity, and pre-pregnancy body mass index were higher in the GDM. The preterm delivery and gestational hypertension increased across the groups from NGT to GIGT to GDM (13.9% vs. 18.8% vs. 25.0%, P<0.01, and 1.9% vs.5.5% vs. 13.5%, P<0.01, respectively). Large for gestational age (LGA) and Neonatal Intensive Care Unit admission rate were higher in order in NGT, GIGT, and GDM (6.2% vs. 15.6% vs. 15.4%, P<0.01, and 12.3% vs. 24.2% vs. 38.5%, P<0.01), but other complications requiring intensive care were not different among the groups, including meconium aspiration syndrome and birth asphyxia.
CONCLUSION
GDM was a risk factor of cesarean section, preterm delivery, and gestational hypertension. In addition, GIGT was positively correlated with gestational hypertension, preterm labor, cesarean section rate, and LGA. This study suggests that there is a need to develop a guideline for Korean pregnant women who were diagnosed with GIGT.

Keyword

Gestational diabetes mellitus; Glucose challenge test; Pregnancy outcomes

MeSH Terms

Asphyxia
Body Mass Index
Cesarean Section
Diabetes, Gestational
Female
Gestational Age
Glucose*
Humans
Hypertension
Hypertension, Pregnancy-Induced
Infant, Newborn
Critical Care
Intensive Care, Neonatal
Mass Screening
Maternal Age
Meconium Aspiration Syndrome
Medical Records
National Health Programs
Obstetric Labor, Premature
Parity
Parturition
Pregnancy
Pregnancy Outcome
Pregnancy, Twin
Pregnant Women*
Retrospective Studies
Risk Factors
Glucose

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