Korean J Pediatr.  2008 Oct;51(10):1085-1089. 10.3345/kjp.2008.51.10.1085.

Comparative study of typical and atypical benign epilepsy with centrotemporal spikes (Rolandic epilepsy)

• Song J
• Lee K
• Chung S

• KMID: 2280316
• DOI: http://doi.org/10.3345/kjp.2008.51.10.1085

Abstract

PURPOSE: This study aims to examine and compare the features of rolandic epilepsy.
METHODS
Of 158 patients selected retrospectively, 116 had typical (group A) and 42 had atypical (group B) rolandic epilepsy, as defined by Worrall's criteria.
RESULTS
The age at onset of the seizures in group Awas 8.6+/-2.0 y and 6.2+/-1.7 y in group B (P>0.05). Among the 40 patients who underwent neuroimaging studies (25 patients in group Aand 15 patients in group B), abnormal findings in group B included ventricular dilatation, mild cortical atrophy, and partial agenesis of corpus callosum. group A had no abnormal findings. The frequency of seizures was 2.0+/-1.0 and 2.3+/-1.2 per month in groups A and B respectively. Seizure control from the initial anticonvulsant treatment was achieved within 3 months in group A, and 3 to 12 months in group B. A 2-year remission rate was noted in 105 patients in group A and in 38 patients in group B. Of these, the recurrence rate after 2 y was 13 in group A and 12 in group B.
CONCLUSION
Age of onset of seizures, gender, frequency of seizures before therapy, and 2-y remission rate were not significantly different in the 2 groups. However, neuroimaging abnormalities, the time to achieving seizure control from the initial anticonvulsant treatment, and the recurrence rate after being seizure-free for 2 y were significantly different in the 2 groups.

Keyword

Benign epilepsy with centrotemporal spikes (BECT); Typical benign rolandic epilepsy; Atypical benign rolandic epilepsy; Worralls criteria

MeSH Terms

Age of Onset
Agenesis of Corpus Callosum
Atrophy
Dilatation
Epilepsy, Rolandic
Humans
Neuroimaging
Recurrence
Retrospective Studies
Seizures
Agenesis of Corpus Callosum