Korean J Pediatr.  2005 Sep;48(9):946-952.

Prevalence and Risk Factors of Vancomycin-Resistant Enterococci (VRE) Colonization in Neonates

• Lee HY
• Kim GH
• Choi JS
• Kim SH
• Choi YY
• Hwang TJ

Abstract

PURPOSE
Vancomycin-resistant enterococci (VRE) are now nosocomial pathogens in Korea. But little is known about the prevalence of stool colonization with VRE in neonates in Korea. So we studied the prevalence and risk factors of VRE colonization in the Neonatal Intensive Care Unit (NICU). METHODS: From January 2000 to December 2004, the medical records of 294 neonates (127 cases of VRE group and 167 cases of non-VRE group, according to the results of stool culture) were reviewed retrospectively. We studied the annual prevalence of VRE and risk factors of VRE colonization in neonates. RESULTS: From 2000 to 2003, the prevalence rate of VRE in NICU increased. After preventing VRE transmission, the prevalence rate of VRE has decreased. CONCLUSION: VRE colonization increased recently. Risk factors of VRE colonization were prematurity, lower birth weight, longer hospitalization and use of vancomycin or 3rd generation cephalosporin, compared with the non-VRE group. To prevent VRE transmission among newborns, aggressive infection control strategies by NICU staffs must be implemented immediately for all babies.

Keyword

VRE colonization; Neonate; Prevalence; Risk factors

MeSH Terms

Birth Weight
Colon*
Hospitalization
Humans
Infant, Newborn*
Infection Control
Intensive Care, Neonatal
Korea
Medical Records
Prevalence*
Retrospective Studies
Risk Factors*
Vancomycin
Vancomycin