The Effect of Post-natal Weight Changes on the Development of Bronchopulmonary Dysplasia in Infants with Respiratory Distress Syndrome

Jhon, Hye One; Kim, Young Min; Hong, Hee Joo; Bae, Chong Woo

Abstract

PURPOSE
The subjects were compared and measured for differences in the aspects of weight changes between the groups that developed bronchopulmonary dysplasia(BPD) after treatment and those that did not, to analyze the relations between the patterns of early weight change after birth and the development of BPD.
METHODS
Retrospective analysis of medical records were performed for birth weight and a corresponding pattern of weight change after birth and a case history of 70 respiratory distress syndrome (RDS) patients born at Kyunghee Medical Center from September 1999 to December 2002. Patients who developed BPD after being treated for RDS were classified as group A and the rest as group B. Each respective group was subdivided into subgroups of birth weight greater and lesser than 1,500 grams.
RESULTS
BPD was observed in 12(17.1%) patients. The duration of initial weight loss and the time to restitution of birth weight were meaningfully longer in group A, and the ratio of initial weight loss to birth weight was significantly greater in group A. On the other hand, when the above comparisons were executed in each group subdivided by birth weight above and below 1500 grams, no significant variables were generated.
CONCLUSION
The postulated points to the duration of initial weight loss and time to restitution of birth weight being significantly longer in groups with BPD. It was also confirmed that this group had a greater ratio of initial weight loss(%) to birth weight were confirmed.