Clin Exp Otorhinolaryngol.  2010 Sep;3(3):172-175.

Benign Pleomorphic Adenoma of the Soft Palate Metastasizing to the Sphenoid Sinus

• Bae CH
• Kim YD
• Song SY

Abstract

A benign pleomorphic adenoma is the most common tumor of the salivary glands. This tumor has the potential to metastasize to bone, the head and neck region, visceral organs and skin. Although there a few reports about a benign pleomorphic adenoma metastasizing to the maxillary sinus in the paranasal sinuses, there are no reports about a metastatic benign pleomorphic adenoma in the sphenoid sinus. We report here on a case of a benign pleomorphic adenoma of the soft palate that metastasized to the sphenoid sinus, and we briefly review the relevant clinical literature.

Keyword

Sphenoid sinus; Pleomorphic adenoma; Metastasis

MeSH Terms

Adenoma, Pleomorphic
Head
Maxillary Sinus
Neck
Neoplasm Metastasis
Palate, Soft
Paranasal Sinuses
Salivary Glands
Skin
Sphenoid Sinus

Figure

• 

  Fig. 1 The axial (A and B) views of the computed tomographic scan before the initial surgery show a round shaped, 4×4 cm sized mass with inhomogeneous low density (arrow) in the soft palate and no mass lesion in the sphenoid sinus. The coronal (C) and axial (D) T2-weighted magnetic resonance imaging sequences at one year after the initial surgery show a round shaped, 1×1 cm sized mass with high signal intensity (arrowhead) at the soft palate and a large mass lesion with high signal intensity (arrow) at the sphenoid sinus that apparently extends to both posterior ethmoid sinuses.

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  Fig. 2 Pathological findings of the mass show abundant myxoid and chondroid stroma with an interspersed island of epithelial cells. There are no atypical mitoses and cellular pleomorphisms. (A) The soft palate at the initial surgery (H&E, ×200). (B) The sphenoid sinus at one year after the initial surgery (H&E, ×200).

Reference

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