Clin Exp Otorhinolaryngol.  2010 Sep;3(3):141-146.

The Effect of Uvula-Preserving Palatopharyngoplasty in Obstructive Sleep Apnea on Globus Sense and Positional Dependency

Affiliations
  • 1Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. yschung@amc.seoul.kr

Abstract


OBJECTIVES
This study investigated the outcomes of uvula-preserving palatopharyngoplasty (UPPPP) in patients with obstructive sleep apnea syndrome (OSAS).
METHODS
Twenty men with obstructive sleep apnea syndrome received the UPPPP operation at our institution. We measured symptom changes after UPPPP using a visual analog scale (VAS), and all patients were examined with polysomnography pre- and post-operatively. 'Surgical success' was defined as reduction in apnea-hypopnea index (AHI) to below 20 events per hour and more than 50% post-operative reduction.
RESULTS
Snoring decreased significantly (6.7+/-2.3 to 3.7+/-2.9 on VAS, P=0.002) but the postoperative globus sense did not differ from that preoperatively (2.0+/-2.4 to 2.1+/-2.7 on VAS, P=0.79). Apnea and apnea-hypopnea indices were significantly reduced after UPPPP (34.7+/-20 to 24.2+/-17.2 events/hour, P=0.029). The surgical success rate was 40% regardless of Friedman stage. There was significant reduction in the AHI on supine sleep in both surgically successful and unsuccessful patient groups.
CONCLUSION
UPPPP may minimize postoperative globus sense and other complications, with a success rate comparable to that of previously reported surgical methods in OSAS patients. In addition, it may reduce the apnea-hypopnea index in the supine sleep position.

Keyword

Obstructive sleep apnea; Uvulopalatopharyngoplasty; Polysomnography; Position

MeSH Terms

Apnea
Dependency (Psychology)
Humans
Male
Polysomnography
Sleep Apnea, Obstructive
Snoring

Figure

  • Fig. 1 Illustration of uvula-preserving palatopharyngoplasty. (A, B) Axial view of the operation field. (A) The classical suture method of uvulopalatopharyngoplasty is associated with a higher rupture risk because of deadspace formation. (B) In our study, the tonsil bed is sutured together and plicated for prevention of deadspace formation. (C) Coronal view of the operation field. Soft tissues are retracted not only anteroposteriorly but also laterally by the tensile force developed in the suture technique.

  • Fig. 2 Photographs of uvula-preserving palatopharyngoplasty. (A) Suturing of the anterior pillar, the tonsil fossa, and the posterior pillar with Vicryl (colored purple) is performed after tonsillectomy. The tonsil fossa is sutured for prevention of rupture caused by deadspace formation. (B) Soft tissues are retracted not only anteroposteriorly but also laterally by the tensile force developed in the suture technique. The preserved uvula will become smaller by contraction of scar tissue on both sides of the musculus palatouvularis and at the lower margin of the tensor palati.


Reference

1. Moon HS. Influence of sleep-related breathing disorders in changes of cardiovascular function. Sleep Med Psychophysiol. 1997; 12. 4(2):129–139.
2. Lee SH, Wang SG, Koo SK, Koo HE, Yun JH, Roh HJ, et al. Long-term polysomnographic findings and subjective results in sleep apnea patients treated with laser assisted uvulopalatoplasty. Korean J Otolaryngol-Head Neck Surg. 2002; 2. 45(2):144–148.
3. Fujita S, Conway W, Zorick F, Roth T. Surgical correction of anatomic azbnormalities in obstructive sleep apnea syndrome: uvulopalatopharyngoplasty. Otolaryngol Head Neck Surg. 1981; Nov–Dec. 89(6):923–934. PMID: 6801592.
4. Rapoport DM, Garay SM, Goldring RM. Nasal CPAP in obstructive sleep apnea: mechanisms of action. Bull Eur Physiopathol Respir. 1983; Nov–Dec. 19(6):616–620. PMID: 6360256.
5. Croft CB, Golding-Wood DG. Uses and complications of uvulopalatopharyngoplasty. J Laryngol Otol. 1990; 11. 104(11):871–875. PMID: 2266310.
Article
6. Haavisto L, Suonpaa J. Complications of uvulopalatopharyngoplasty. Clin Otolaryngol Allied Sci. 1994; 6. 19(3):243–247. PMID: 7923849.
Article
7. Hagert B, Wikblad K, Odkvist L, Wahren LK. Side effects after surgical treatment of snoring. ORL J Otorhinolaryngol Relat Spec. 2000; Mar–Apr. 62(2):76–80. PMID: 10729796.
Article
8. Goh YH, Mark I, Fee WE Jr. Quality of life 17 to 20 years after uvulopalatopharyngoplasty. Laryngoscope. 2007; 3. 117(3):503–506. PMID: 17334312.
Article
9. Back GW, Nadig S, Uppal S, Coatesworth AP. Why do we have a uvula?: literature review and a new theory. Clin Otolaryngol Allied Sci. 2004; 12. 29(6):689–693. PMID: 15533161.
Article
10. Han D, Ye J, Lin Z, Wang J, Zhang Y. Revised uvulopalatopharyngoplasty with uvula preservation and its clinical study. ORL J Otorhinolaryngol Relat Spec. 2005; 67(4):213–219. PMID: 16103738.
Article
11. Gastaut H, Tassinari CA, Duron B. Polygraphic study of the episodic diurnal and nocturnal (hypnic and respiratory) manifestations of the Pickwick syndrome. Brain Res. 1966; 2. 1(2):167–186. PMID: 5923125.
Article
12. Cartwright R, Ristanovic R, Diaz F, Caldarelli D, Alder G. A comparative study of treatments for positional sleep apnea. Sleep. 1991; 12. 14(6):546–552. PMID: 1798889.
Article
13. Fujita S, Conway WA, Zorick FJ, Sicklesteel JM, Roehrs TA, Wittig RM, et al. Evaluation of the effectiveness of uvulopalatopharyngoplasty. Laryngoscope. 1985; 1. 95(1):70–74. PMID: 3965833.
Article
14. Sher AE, Schechtman KB, Piccirillo JF. The efficacy of surgical modifications of the upper airway in adults with obstructive sleep apnea syndrome. Sleep. 1996; 2. 19(2):156–177. PMID: 8855039.
Article
15. Janson C, Gislason T, Bengtsson H, Eriksson G, Lindberg E, Lindholm CE, et al. Long-term follow-up of patients with obstructive sleep apnea treated with uvulopalatopharyngoplasty. Arch Otolaryngol Head Neck Surg. 1997; 3. 123(3):257–262. PMID: 9076230.
Article
16. Schechtman KB, Sher AE, Piccirillo JF. Methodological and statistical problems in sleep apnea research: the literature on uvulopalatopharyngoplasty. Sleep. 1995; 10. 18(8):659–666. PMID: 8560132.
Article
17. Friedman M, Ibrahim H, Joseph NJ. Staging of obstructive sleep apnea/hypopnea syndrome: a guide to appropriate treatment. Laryngoscope. 2004; 3. 114(3):454–459. PMID: 15091218.
Article
18. Finkelstein Y, Meshorer A, Talmi YP, Zohar Y, Brenner J, Gal R. The riddle of the uvula. Otolaryngol Head Neck Surg. 1992; 9. 107(3):444–450. PMID: 1408233.
Article
19. Kezirian EJ, Weaver EM, Yueh B, Deyo RA, Khuri SF, Daley J, et al. Incidence of serious complications after uvulopalatopharyngoplasty. Laryngoscope. 2004; 3. 114(3):450–453. PMID: 15091217.
Article
20. Mortimore IL, Bradley PA, Murray JA, Douglas NJ. Uvulopalatopharyngoplasty may compromise nasal CPAP therapy in sleep apnea syndrome. Am J Respir Crit Care Med. 1996; 12. 154(6 Pt 1):1759–1762. PMID: 8970367.
Article
21. Han F, Song W, Li J, Zhang L, Dong X, He Q. Influence of UPPP surgery on tolerance to subsequent continuous positive airway pressure in patients with OSAHS. Sleep Breath. 2006; 3. 10(1):37–42. PMID: 16432757.
Article
Full Text Links
  • CEO
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr