Clin Exp Otorhinolaryngol.  2014 Mar;7(1):63-65.

Aggravation of Relapsing Polychondritis due to the Infection and Its Manifestation on a Nasal Tip Graft

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Bundang Jesaeng General Hospital, Daejin Medical Center, Seongnam, Korea. renalcho@hanmail.net
  • 2Department of Dermatology, Korea University College of Medicine, Seoul, Korea.

Abstract

Relapsing polychondritis (RP) is an uncommon systemic disease that is characterized by episodic and progressive inflammation of the cartilaginous structures, which can be very debilitating and in some instances life-threatening. The pathogenic pathways of RP are largely unknown. However, several hypothesis have been suggested. We had an interesting case of aggravation of RP due to the infection. Graft cartilage on the nasal tip was affected by RP also. This case can give a clue of revealing the pathogenesis of RP. We introduce a case with a review of the literature.

Keyword

Relapsing polychondritis; Nose; Cartilage; Antibody; Foreign-body reaction

MeSH Terms

Cartilage
Foreign-Body Reaction
Inflammation
Nose
Polychondritis, Relapsing*
Transplants*

Figure

  • Fig. 1 Photograph of relapsing polychondritis involved site (ear, nose, and filler injected lips). (A) Frontal view, (B) lateral view.

  • Fig. 2 Improvement of relapsing polychondritis on ear and nose (4th hospital day).


Reference

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