Korean J Pain.  2012 Jul;25(3):143-150. 10.3344/kjp.2012.25.3.143.

Spinal Cord Stimulation in Pain Management: A Review

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, School of Dentistry, Kyungpook National University, Daegu, Korea. jeon68@knu.ac.kr

Abstract

Spinal cord stimulation has become a widely used and efficient alternative for the management of refractory chronic pain that is unresponsive to conservative therapies. Technological improvements have been considerable and the current neuromodulation devices are both extremely sophisticated and reliable in obtaining good results for various clinical situations of chronic pain, such as failed back surgery syndrome, complex regional pain syndrome, ischemic and coronary artery disease. This technique is likely to possess a savings in costs compared with alternative therapy strategies despite its high initial cost. Spinal cord stimulation continues to be a valuable tool in the treatment of chronic disabling pain.

Keyword

angina pectoris; complex regional pain syndromes; failed back surgery syndrome; ischemia; spinal cord stimulation

MeSH Terms

Angina Pectoris
Chronic Pain
Complex Regional Pain Syndromes
Coronary Artery Disease
Failed Back Surgery Syndrome
Income
Ischemia
Spinal Cord
Spinal Cord Stimulation

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Reference

1. Melzack R, Wall PD. Pain mechanisms: a new theory. Science. 1965; 150:971–979. PMID: 5320816.
Article
2. Shealy CN, Mortimer JT, Reswick JB. Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report. Anesth Analg. 1967; 46:489–491. PMID: 4952225.
3. Burchiel KJ, Anderson VC, Wilson BJ, Denison DB, Olson KA, Shatin D. Prognostic factors of spinal cord stimulation for chronic back and leg pain. Neurosurgery. 1995; 36:1101–1110. PMID: 7643988.
Article
4. North RB. Psychological criteria are outcome measures as well as prognostic factors. Pain Forum. 1996; 5:111–114.
Article
5. Kemler MA, Barendse GA, van Kleef M, de Vet HC, Rijks CP, Furnée CA, et al. Spinal cord stimulation in patients with chronic reflex sympathetic dystrophy. N Engl J Med. 2000; 343:618–624. PMID: 10965008.
Article
6. Barolat G. Spinal cord stimulation for chronic pain management. Arch Med Res. 2000; 31:258–262. PMID: 11036175.
Article
7. Kemler MA, Raphael JH, Bentley A, Taylor RS. The cost-effectiveness of spinal cord stimulation for complex regional pain syndrome. Value Health. 2010; 13:735–742. PMID: 20561326.
Article
8. Hornberger J, Kumar K, Verhulst E, Clark MA, Hernandez J. Rechargeable spinal cord stimulation versus non-rechargeable system for patients with failed back surgery syndrome: a cost-consequences analysis. Clin J Pain. 2008; 24:244–252. PMID: 18287831.
Article
9. Cui JG, Meyerson BA, Sollevi A, Linderoth B. Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation. Neurosci Lett. 1998; 247:183–186. PMID: 9655623.
Article
10. Dubuisson D. Effect of dorsal-column stimulation on gelatinosa and marginal neurons of cat spinal cord. J Neurosurg. 1989; 70:257–265. PMID: 2913223.
Article
11. Stiller CO, Cui JG, O'Connor WT, Brodin E, Meyerson BA, Linderoth B. Release of gamma-aminobutyric acid in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats. Neurosurgery. 1996; 39:367–374. PMID: 8832675.
12. Linderoth B, Gazelius B, Franck J, Brodin E. Dorsal column stimulation induces release of serotonin and substance P in the cat dorsal horn. Neurosurgery. 1992; 31:289–296. PMID: 1381066.
Article
13. Ren B, Linderoth B, Meyerson BA. Effects of spinal cord stimulation on the flexor reflex and involvement of supraspinal mechanisms: an experimental study in mononeuropathic rats. J Neurosurg. 1996; 84:244–249. PMID: 8592227.
Article
14. Meyerson BA, Ren B, Herregodts P, Linderoth B. Spinal cord stimulation in animal models of mononeuropathy: effects on the withdrawal response and the flexor reflex. Pain. 1995; 61:229–243. PMID: 7659433.
Article
15. Larson SJ, Sances A Jr, Riegel DH, Meyer GA, Dallmann DE, Swiontek T. Neurophysiological effects of dorsal column stimulation in man and monkey. J Neurosurg. 1974; 41:217–223. PMID: 4210432.
Article
16. Bantli H, Bloedel JR, Thienprasit P. Supraspinal interactions resulting from experimental dorsal column stimulation. J Neurosurg. 1975; 42:296–300. PMID: 1117327.
Article
17. Oakley JC, Prager JP. Spinal cord stimulation: mechanisms of action. Spine (Phila Pa 1976). 2002; 27:2574–2583. PMID: 12435996.
18. Linderoth B, Fedorcsak I, Meyerson BA. Peripheral vasodilatation after spinal cord stimulation: animal studies of putative effector mechanisms. Neurosurgery. 1991; 28:187–195. PMID: 1671794.
Article
19. Linderoth B, Herregodts P, Meyerson BA. Sympathetic mediation of peripheral vasodilation induced by spinal cord stimulation: animal studies of the role of cholinergic and adrenergic receptor subtypes. Neurosurgery. 1994; 35:711–719. PMID: 7808615.
Article
20. Holsheimer J, Wesselink WA. Optimum electrode geometry for spinal cord stimulation: the narrow bipole and tripole. Med Biol Eng Comput. 1997; 35:493–497. PMID: 9374053.
Article
21. Oakley JC, Espinosa F, Bothe H, McKean J, Allen P, Burchiel K, et al. Transverse tripolar spinal cord stimulation: results of an international multicenter study. Neuromodulation. 2006; 9:192–203. PMID: 22151707.
Article
22. Chincholkar M, Eldabe S, Strachan R, Brookes M, Garner F, Chadwick R, et al. Prospective analysis of the trial period for spinal cord stimulation treatment for chronic pain. Neuromodulation. 2011; 14:523–528. PMID: 21854495.
Article
23. Taylor RS, Van Buyten JP, Buchser E. Spinal cord stimulation for chronic back and leg pain and failed back surgery syndrome: a systematic review and analysis of prognostic factors. Spine (Phila Pa 1976). 2005; 30:152–160. PMID: 15626996.
Article
24. North RB, Kidd DH, Farrokhi F, Piantadosi SA. Spinal cord stimulation versus repeated lumbosacral spine surgery for chronic pain: a randomized, controlled trial. Neurosurgery. 2005; 56:98–106. PMID: 15617591.
Article
25. North RB, Ewend MG, Lawton MT, Kidd DH, Piantadosi S. Failed back surgery syndrome: 5-year follow-up after spinal cord stimulator implantation. Neurosurgery. 1991; 28:692–699. PMID: 1831547.
Article
26. Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, et al. Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome. Pain. 2007; 132:179–188. PMID: 17845835.
Article
27. Kemler MA, De Vet HC, Barendse GA, Van Den Wildenberg FA, Van Kleef M. The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: two years\' follow-up of the randomized controlled trial. Ann Neurol. 2004; 55:13–18. PMID: 14705107.
Article
28. Kemler MA, de Vet HC, Barendse GA, van den Wildenberg FA, van Kleef M. Effect of spinal cord stimulation for chronic complex regional pain syndrome Type I: five-year final follow-up of patients in a randomized controlled trial. J Neurosurg. 2008; 108:292–298. PMID: 18240925.
Article
29. Stanton-Hicks M. Complex regional pain syndrome: manifestations and the role of neurostimulation in its management. J Pain Symptom Manage. 2006; 31(4 Suppl):S20–S24. PMID: 16647591.
Article
30. Murphy DF, Giles KE. Dorsal column stimulation for pain relief from intractable angina pectoris. Pain. 1987; 28:365–368. PMID: 3494978.
Article
31. Murray S, Carson KG, Ewings PD, Collins PD, James MA. Spinal cord stimulation significantly decreases the need for acute hospital admission for chest pain in patients with refractory angina pectoris. Heart. 1999; 82:89–92. PMID: 10377316.
Article
32. TenVaarwerk IA, Jessurun GA, DeJongste MJ, Andersen C, Mannheimer C, Eliasson T, et al. The Working Group on Neurocardiology. Clinical outcome of patients treated with spinal cord stimulation for therapeutically refractory angina pectoris. Heart. 1999; 82:82–88. PMID: 10377314.
Article
33. Mannheimer C, Eliasson T, Augustinsson LE, Blomstrand C, Emanuelsson H, Larsson S, et al. Electrical stimulation versus coronary artery bypass surgery in severe angina pectoris: the ESBY study. Circulation. 1998; 97:1157–1163. PMID: 9537342.
Article
34. Andréll P, Yu W, Gersbach P, Gillberg L, Pehrsson K, Hardy I, et al. Long-term effects of spinal cord stimulation on angina symptoms and quality of life in patients with refractory angina pectoris--results from the European Angina Registry Link Study (EARL). Heart. 2010; 96:1132–1136. PMID: 20483898.
Article
35. Neri Serneri GG, Boddi M, Arata L, Rostagno C, Dabizzi P, Coppo M, et al. Silent ischemia in unstable angina is related to an altered cardiac norepinephrine handling. Circulation. 1993; 87:1928–1937. PMID: 8504506.
Article
36. McCance AJ, Thompson PA, Forfar JC. Increased cardiac sympathetic nervous activity in patients with unstable coronary heart disease. Eur Heart J. 1993; 14:751–757. PMID: 8325300.
Article
37. Norrsell H, Eliasson T, Mannheimer C, Augustinsson LE, Bergh CH, Andersson B, et al. Effects of pacing-induced myocardial stress and spinal cord stimulation on whole body and cardiac norepinephrine spillover. Eur Heart J. 1997; 18:1890–1896. PMID: 9447316.
Article
38. Foreman RD, Linderoth B, Ardell JL, Barron KW, Chandler MJ, Hull SS Jr, et al. Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris. Cardiovasc Res. 2000; 47:367–375. PMID: 10946073.
Article
39. Murray S, Collins PD, James MA. Neurostimulation treatment for angina pectoris. Heart. 2000; 83:217–220. PMID: 10648501.
Article
40. Cook AW, Oygar A, Baggenstos P, Pacheco S, Kleriga E. Vascular disease of extremities. Electric stimulation of spinal cord and posterior roots. N Y State J Med. 1976; 76:366–368. PMID: 1062688.
41. Amann W, Berg P, Gersbach P, Gamain J, Raphael JH, Ubbink DT, et al. Spinal cord stimulation in the treatment of non-reconstructable stable critical leg ischaemia: results of the European Peripheral Vascular Disease Outcome Study (SCS-EPOS). Eur J Vasc Endovasc Surg. 2003; 26:280–286. PMID: 14509891.
Article
42. Jivegård LE, Augustinsson LE, Holm J, Risberg B, Ortenwall P. Effects of spinal cord stimulation (SCS) in patients with inoperable severe lower limb ischaemia: a prospective randomised controlled study. Eur J Vasc Endovasc Surg. 1995; 9:421–425. PMID: 7633987.
Article
43. Claeys LG, Horsch S. Transcutaneous oxygen pressure as predictive parameter for ulcer healing in endstage vascular patients treated with spinal cord stimulation. Int Angiol. 1996; 15:344–349. PMID: 9127776.
44. Klomp HM, Spincemaille GH, Steyerberg EW, Habbema JD, van Urk H. ESES Study Group. Spinal-cord stimulation in critical limb ischaemia: a randomised trial. Lancet. 1999; 353:1040–1044. PMID: 10199350.
Article
45. Petrakis IE, Sciacca V. Spinal cord stimulation in critical limb ischemia of the lower extremities: our experience. J Neurosurg Sci. 1999; 43:285–293. PMID: 10864391.
46. Ubbink DT, Vermeulen H. Spinal cord stimulation for non-reconstructable chronic critical leg ischaemia. Cochrane Database Syst Rev. 2005; (3):CD004001. PMID: 16034919.
Article
47. Horsch S, Claeys L. Epidural spinal cord stimulation in the treatment of severe peripheral arterial occlusive disease. Ann Vasc Surg. 1994; 8:468–474. PMID: 7811584.
Article
48. Pedrini L, Magnoni F. Spinal cord stimulation for lower limb ischemic pain treatment. Interact Cardiovasc Thorac Surg. 2007; 6:495–500. PMID: 17669915.
Article
49. Spincemaille GH, de Vet HC, Ubbink DT, Jacobs MJ. The results of spinal cord stimulation in critical limb ischaemia: a review. Eur J Vasc Endovasc Surg. 2001; 21:99–105. PMID: 11237781.
Article
50. Manca A, Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, et al. Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial). Eur J Pain. 2008; 12:1047–1058. PMID: 18359255.
Article
51. Yu W, Maru F, Edner M, Hellström K, Kahan T, Persson H. Spinal cord stimulation for refractory angina pectoris: a retrospective analysis of efficacy and cost-benefit. Coron Artery Dis. 2004; 15:31–37. PMID: 15201618.
Article
52. Turner JA, Loeser JD, Deyo RA, Sanders SB. Spinal cord stimulation for patients with failed back surgery syndrome or complex regional pain syndrome: a systematic review of effectiveness and complications. Pain. 2004; 108:137–147. PMID: 15109517.
Article
53. Mekhail NA, Mathews M, Nageeb F, Guirguis M, Mekhail MN, Cheng J. Retrospective review of 707 cases of spinal cord stimulation: indications and complications. Pain Pract. 2011; 11:148–153. PMID: 21371254.
Article
54. Cameron T. Safety and efficacy of spinal cord stimulation for the treatment of chronic pain: a 20-year literature review. J Neurosurg. 2004; 100(3 Suppl Spine):254–267. PMID: 15029914.
Article
55. Barolat G. Experience with 509 plate electrodes implanted epidurally from C1 to L1. Stereotact Funct Neurosurg. 1993; 61:60–79. PMID: 8197329.
Article
56. McDonald M, Grabsch E, Marshall C, Forbes A. Single-versus multiple-dose antimicrobial prophylaxis for major surgery: a systematic review. Aust N Z J Surg. 1998; 68:388–396. PMID: 9623456.
Article
57. Bedder MD, Bedder HF. Spinal cord stimulation surgical technique for the nonsurgically trained. Neuromodulation. 2009; 12(Suppl 1):1–19. PMID: 22151467.
Article
58. Eldrige JS, Weingarten TN, Rho RH. Management of cerebral spinal fluid leak complicating spinal cord stimulator implantation. Pain Pract. 2006; 6:285–288. PMID: 17129310.
Article
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