Korean J Pediatr Hematol Oncol.  1998 Apr;5(1):81-88.

An Analytic Study for Incidence of Childhood Leukemia in Pusan City, Korea

Affiliations
  • 1Department of Pediatrics, Inje University College of Medicine, Korea.
  • 2Department of Pediatrics, Kosin Medical Center, Korea.
  • 3Department of Pediatrics, Dong-A University College of Medicine, Korea.
  • 4Department of Pediatrics, Pusan University College of Medicine, Korea.
  • 5Department of Preventive Medicine, Inje University College of Medicine, Korea.
  • 6Department of Preventive Medicine, Pusan Dae Dong General Hospital, Korea.
  • 7Department of Preventive Medicine, Dong-Eui Medical Center, Korea.
  • 8Department of Preventive Medicine, St. Benedict Hospital, Korea.
  • 9Department of Preventive Medicine, Choon Hae Hospital, Korea.
  • 10Department of Preventive Medicine, Gwanghye Hospital, Korea.
  • 11Department of Preventive Medicine, Pusan Adventist Hospital, Korea.
  • 12Department of Preventive Medicine, Wallace Memorial Baptist Hospital, Korea.
  • 13Department of Preventive Medicine, Il Sin Christian Hospital, Korea.
  • 14Department of Preventive Medicine, Pusan City Medical Center, Korea.
  • 15Department of Preventive Medicine, Maryknoll Hospital, Korea.
  • 16Department of Preventive Medicine, Bong Seng Memorial Hospital, Korea.

Abstract

BACKGROUND: Cancer is the second cause of childhood death following accident, and leukemia is the most frequent childhood cancer in Korea. For the desirable control of childhood leukemia, of which the mortality is still high, the basic data for the incidence has a great importance. This is the second report from the data during 1991~1995 following the first one that analyzed the data from 328 cases of childhood leukemia during 1981~1990 in the same area, Pusan city, Korea.
METHODS
The data were obtained from 138 new cases(84 males and 54 females from 0 to 15 years old) of childhood leukemia who had been living in the city of Pusan and were admitted to the 4 university hospitals and 11 general hospitals from 1991 to 1995. The cases were confirmed by CBC and bone marrow examination.
RESULTS
The crude annual incidence rate per 100,000 population varied 1.50~5.30, 2.59~6.00 and 1.58~2.61 in the age group of 0~4 years, 5~9 years and 10~14 years, respectively. The standardized annual incidence rate per 100,000 population varied from 2.05 to 3.46(male 2.96~4.89, female 0.98~3.57). Sex ratio(male to female) was 1.58:1, 1.44:1, and 1.82:1 in total cases, ALL and AML, respectively, while incalculable in CML. By the major types of childhood leukemia, the cases were composed of 105 ALL (76.1%), 31 AML(22.5%), 2 CML(1.4%).
CONCLUSION
It was concluded that the annual incidence rate of childhood leukemia per 100,000 population in Pusan city during 1991~1995 was similar to that of previous report during 1981~1990, while the proportion of ALL had tendency to increase up to that of United States, in contrast to the low proportions of ALL in the previous reports.

Keyword

Pusan city; Childhood leukemia; ALL; AML; CML; Age and sex adjusted annual incidence rate; Standardized annual incidence rate

MeSH Terms

Bone Marrow Examination
Busan*
Female
Hospitals, General
Hospitals, University
Humans
Incidence*
Korea*
Leukemia*
Male
Mortality
United States
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