Korean J Otorhinolaryngol-Head Neck Surg.  2013 Mar;56(3):159-162. 10.3342/kjorl-hns.2013.56.3.159.

A Case of Primary Thyroid Lymphoma Originated from Thyroid Gland

• Lee HJ
• Shim HS
• Kim JP
• Woo SH

• KMID: 2277876
• DOI: http://doi.org/10.3342/kjorl-hns.2013.56.3.159

Abstract

We present a case of a 53-year-old woman with a rapidly growing neck mass. She had one-year history of hypothyroidism associatied with Hashimoto thyroiditis. She had noticed progressive dyspnea with rapid enlargement of the thyroid gland over a month. An incisional biopsy of the thyroid gland for combined pathology and immunohistochemistry revealed diffuse large B cell non-Hodgkin's lymphoma. A combined chemotherapy including cyclophosphamide, doxorubicin, vincristine, prednisone plus rituximab (R-CHOP) was initiated, which dramatically shrunk the tumor and completely resolved the compression symptoms within a few days. Here we report on a case of thyroid lymphoma with a review of the relevant literature.

Keyword

Combination chemotherapy; Hashimoto thyroiditis; Immunohistochemistry; Lymphoma; Thyroid

MeSH Terms

Antibodies, Monoclonal, Murine-Derived
Biopsy
Cyclophosphamide
Doxorubicin
Drug Therapy, Combination
Dyspnea
Female
Hashimoto Disease
Humans
Hypothyroidism
Immunohistochemistry
Lymphoma
Lymphoma, Non-Hodgkin
Neck
Prednisone
Thyroid Gland
Vincristine
Rituximab
Antibodies, Monoclonal, Murine-Derived
Cyclophosphamide
Doxorubicin
Prednisone
Vincristine