Korean J Otorhinolaryngol-Head Neck Surg.  2015 Mar;58(3):217-219. 10.3342/kjorl-hns.2015.58.3.217.

Glottic Infection by Herpes Simplex Virus in an Irradiated Patient

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Otorhinolaryngology-Head and Neck Surgery, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. entist@naver.com

Abstract

Herpetic laryngitis is extremely rare in healthy adults. The local factors that increase susceptibility to herpes simplex virus include irradiation on the head and neck area. A 66-year-old man who had history of supraglottic cancer had voice change 4 years after the radiotherapy. On laryngscopic examination, the erosive mucosal lesion was found on his left vocal fold. A pathologic examination of the lesion by suspension laryngoscopy revealed that the lesion was herpetic laryngitis, which was confirmed by immunohistochemical stain as herpes simplex virus. Herpetic laryngitis should be in the index of differential diagnosis in patients with laryngitis who have the history of irradiation on the neck.

Keyword

Glottic cancer; Herpes simplex virus; Laryngitis; Radiotherapy

MeSH Terms

Adult
Aged
Diagnosis, Differential
Head
Humans
Laryngitis
Laryngoscopy
Neck
Radiotherapy
Simplexvirus*
Vocal Cords
Voice
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