Korean J Pathol.  2006 Apr;40(2):148-150.

Inflammatory Myofibroblastic Tumor of the Stomach: A Case Report

Affiliations
  • 1Department of Pathology, Inha University College of Medicine, Inchon, Korea. jmkpath@inha.ac.kr
  • 2Department of Surgery, Inha University College of Medicine, Inchon, Korea.
  • 3Inha Research Institute for Medical Science, Inchon, Korea.

Abstract

Inflammatory myofibroblastic tumor of the stomach is a rare tumor-like, benign disease with an uncertain pathogenesis. A 15-year-old male presented with epigastric pain. Endoscopic ultrasonography revealed a 2.3 cm sized ovoid intramuscular mass in the lower body of the stomach at the lesser curvature. Histologically, the tumor was composed of smooth muscle actin positive- and vimentin positive spindle cells and there were a large number of lymphocytes, plasma cells and histiocytes in the fibrotic background. The spindle cells were also positive for ALK1, but negative for EBV in situ hybridization.

Keyword

Inflammatory myofibroblastic tumor; Inflammatory pseudotumor; ALK; Stomach

MeSH Terms

Actins
Adolescent
Endosonography
Granuloma, Plasma Cell
Herpesvirus 4, Human
Histiocytes
Humans
In Situ Hybridization
Lymphocytes
Male
Muscle, Smooth
Myofibroblasts*
Plasma Cells
Stomach*
Vimentin
Actins
Vimentin
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