Korean J Otorhinolaryngol-Head Neck Surg.
2010 Sep;53(9):582-584. 10.3342/kjorl-hns.2010.53.9.582.
A Case of Epithelial-Myoepithelial Carcinoma in Left Submandibular Gland
- Affiliations
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- 1Ulsan Hana ORL Hospital, Ulsan, Korea.
- 2Department of Otolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea. hspark1@dau.ac.kr
- 3Department of Pathology, Dong-A University College of Medicine, Busan, Korea.
- KMID: 2277166
- DOI: http://doi.org/10.3342/kjorl-hns.2010.53.9.582
Abstract
- Epithelial myoepithelial carcinoma is a rare tumor with slightly less than one percent of salivary gland neoplasm. Histologically, the carcinomas are characterized by a mixture of trabecular structure with outer myoepithelial cells and inner ductal cells, which are confirmed by electron microscopy and immunohistochemistry. Although this neoplasm exhibits high degree of cellular differentiation histologically, it is classified into low grade carcinoma because of its locally infiltrative, destructive growth pattern, and tendency to metastasize. We report a 45-year-old woman with epithelial-myoepithelial carcinoma arising from a submandubular gland, one of the most unusual locations.
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