Verrucous Carcinoma of Nasal Vestibule: A Case Report

Koo, Soo Kweon; Kim, Hyun Kyu; Han, Cheol Woo; Kim, Tae Heon

Abstract

Verrucous carcinoma, an atypical variant of squamous cell carcinoma that is well-differentiated, is known to invade locally with rare metastasis. It was first reported by Ackerman in 1948 and has been reported in the areas of the head and neck and the external genitalia. A case of endonasal verrucous carcinoma was first reported by Krause. Cases of the sinus were reported to have occurred in the ostium of maxillary sinus and frontal sinus, and there has also been a reported case of a verrucous carcinoma that invaded the subnasal, which originated from the hard palate. However, no such case of verrucous carcinoma invasion originating from the nasal vestibule has been reported. Verrucous carcinomas are often clinically malignant, yet pathohistologically benign, thus, unlike most squamous cell carcinomas, they are of a low-risk group with rare metastasis, few recurrences, and good prognosis with proper treatment. In some cases of verrucous carcinoma treated with radiotherapy, anaplastic variations occur, thus surgical removal is known to be the treatment of choice. The authors report a recent case of verrucous carcinoma that originated from the nasal vestibule which was surgically removed and treated with adjuvant radiotherapy.