Korean J Otolaryngol-Head Neck Surg.  2005 Jan;48(1):98-100.

A Case of MALToma Involving the Thyroid Gland

• Chang JH
• Kim HS
• Lim JY
• Choi HS

Abstract

Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin's lymphomas of B and T cell types, as well as Hodgkin's lymphomas. Recently, mucosa-associated lymphoid tissue lymphoma (MALToma) are recognized as a B cell subset of non-stomach origin. However, they may also occur in lungs, salivary glands, skin, and other sites, including the thyroid. Thyroid MALTomas make up about 9% of all non-gastrointestinal tract tyroid lymophomas. MALTomas are thought to develop from acquired lymphocytic tissue during the course of a chronic inflammatory or autoimmune process. In the thyroid, which is normally devoid of lymphocytic tissues, chronic autoimmune thyroiditis (Hashimoto's disease) has been associated with an increased risk of lymphoma, including MALT type. We report a case of MALToma of the thyroid.

Keyword

Thyroid gland; Mucosa-associated lymphoid tissue lymphoma

MeSH Terms

Hodgkin Disease
Lung
Lymphoma
Lymphoma, B-Cell, Marginal Zone
Lymphoma, Non-Hodgkin
Salivary Glands
Skin
Thyroid Gland*
Thyroiditis, Autoimmune