Korean J Otolaryngol-Head Neck Surg.  2004 Feb;47(2):174-176.

A Case of Fibrous Histiocytoma in Parotid Gland

• Chung SW
• Chu HS
• Woo JS
• Jung KY

Abstract

Fibrous histiocytoma is a tumor of a biphasic cell population of fibroblasts and histiocytes. It usually occurs in the sun-exposed skin and orbital tissue but it has also been found in the upper aerodigestive tract, salivary gland, and deep layers of scalps and face. Fibrous histiocytoma in the parotid gland is extremely rare. It must be distinguished from other spindle cell tumors of parotid gland, particularly those of epithelial and myoepithelial origins. In immunohistochemical studies, antibody markers against vimentin and smooth muscle-specific actin lead to the diagnosis of fibrous histiocytoma. The malignant fibrous histiocytoma can be differentiated by its histopathology, since it consists of pleomorphism of cells, abundant mitotic figure, atypic mitotic figure and other tissue invasion. The clinical features such as rapid growth and distant organ metastasis allow a diagnosis of malignant variants. Treatment of benign fibrous histiocytoma can be made by a wide local excision without the sacrifice of near organs.

Keyword

Histiocytoma; Fibrous; Parotid gland

MeSH Terms

Actins
Diagnosis
Fibroblasts
Histiocytes
Histiocytoma
Histiocytoma, Benign Fibrous*
Histiocytoma, Malignant Fibrous
Neoplasm Metastasis
Orbit
Parotid Gland*
Salivary Glands
Scalp
Skin
Vimentin
Actins
Vimentin