Analysis on the Treatment Outcome of Early Glottic Cancer

Yang, Jin Seok; Lee, Yoon Se; Kim, Beom Gyu; Choi, Seung Ho; Nam, Soon Yuhl; Kim, Sang Yoon

Abstract

BACKGROUND AND OBJECTIVES
The choice of the treatment in early glottic cancer depends on various factors. To evaluate the differences between the radiotherapy and conservation, laryngeal surgery including laser cordectomy, vertical hemilaryngectomy and supracricoid partial laryngectomy in early glottic cancer is thought to be valuable in defining the exact indication and recommending treatment modality on the early glottic cancer patients. MATERIALS AND METHOD: The medical records of 136 patients with glottic TisN0, T1N0 or T2N0 cancer diagnosed at Asan medical center, University of Ulsan college of medicine from May, 1989 to July, 2001 were retrospectively reviewed. The five-year survival rate, local control rate, and expenses were compared among the radiation therapy group, the laser cordectomy group and the partial laryngectomy group. RESULTS: Surgical management and radiotherapy showed 97.2% and 96.0% 5-year survival rate, respectively. And laser cordectomy and partial laryngectomy had 95.0% and 92.9% local control rate, respectively while radiotherapy got 87.6% local control rate. Laser cordectomy costs lower than any other treatment. CONCLUSION: On the basis of the oncologic result, both the surgery and radiotherapy had the similar results, but surgical management seemed to show more organ preservation rate. Besides, in anterior commissure invasion, there was no significant difference between the survival and local control rate between surgery and radiotherapy.