Korean J Otolaryngol-Head Neck Surg.  2003 Jan;46(1):81-84.

A Case of Extramedullary Plasmacytoma Originated from the Nasal Septum

• Hong SC
• Lee SW
• Chang C
• Shin HS

Abstract

The extramedullary plasmacytoma is a neoplastic proliferation of plasmacytes in reticuloendothelial tissues, and it occurs most commonly in the head and neck area, especially in the upper respiratory tract and the oral cavity. The most frequent sites are the paranasal sinuses, nasal cavity and nasopharynx. If histologic diagnosis of plasmacytoma is confirmed, all screening tests are necessary to rule out multiple myeloma. The treatment and prognosis are different according to sites where the extramedullary plasmacytoma is originated. We experienced a case of extramedullary plasmacytoma that originated from the septum in a 60-year-old man. After the embolization, endoscopicgical removal of the mass was carried out. Its histopathologic finging revealed the plasmacytoma of lambda type. Systemic evaluations were done immediately and there was no evidence of systemic involvement. Additional radiotherapy (50 Gy) was performed. After ten months of treatment, there was no evidence of recurrence. So we report this case with a review of the literature.

Keyword

Plasmacytoma; Nasal septum

MeSH Terms

Diagnosis
Head
Humans
Mass Screening
Middle Aged
Mouth
Multiple Myeloma
Nasal Cavity
Nasal Septum*
Nasopharynx
Neck
Paranasal Sinuses
Plasma Cells
Plasmacytoma*
Prognosis
Radiotherapy
Recurrence
Respiratory System