Korean J Otolaryngol-Head Neck Surg.  2002 Apr;45(4):380-382.

Effect of Smoking to Warthin's Tumor of Parotid Gland

• Woo JS
• Lee HM
• Kim HY
• Choi JH
• Jung JY
• Jung KY
• Choi JO
• Hwang SJ

Abstract

BACKGROUND AND OBJECTIVES: Warthin's tumor is known to be the second most common benign tumor of the parotid gland. Recent reports describe epidemiological changes of Warthin's tumor in other nations, however its clinical manifestations are still the mainstay of domestic studies. The purpose of this study is to investigate the prevalence of this tumor from various standpoints and the correlation between smoking and the development of Warthin's tumor. MATERIALS AND METHOD: A retrospective review of medical records was carried out on 135 patients who underwent parotid surgery from January 1991 through December 2000 and were diagnosed pathologically as Warthin's tumor and pleomorphic adenoma.
RESULTS
The overall incidences of Warthin's tumor and pleomorphic adenoma of parotid gland were 15% and 57% of all parotid tumors, respectively. The male to female ratio for Warthin's tumor was 3.8:1 and the median age at presentation was 57.4 years old. Smoking is significantly associated with the development of Warthin's tumor (p=0.0054).
CONCLUSIONS
In this study, smoking seems to be a risk factor in the pathogenesis of Warthin's tumor.

Keyword

Warthin's tumor; Parotid gland; Smoking

MeSH Terms

Adenoma, Pleomorphic
Female
Humans
Incidence
Male
Medical Records
Parotid Gland*
Prevalence
Retrospective Studies
Risk Factors
Smoke*
Smoking*
Smoke