Korean J Obstet Gynecol.  2012 Mar;55(3):187-191. 10.5468/KJOG.2012.55.3.187.

A case of malignant fibrothecoma of the ovary

• Kim SK
• Park JW

• KMID: 2274125
• DOI: http://doi.org/10.5468/KJOG.2012.55.3.187

Abstract

Fibrothecomas are mesenchymal tumors deriving from the ovarian stromal and consisting of theca-like elements and fibrous tissue. They are common, but their malignant counterpart is extraordinarily rare. Classical malignant fibrothecomas are said to show four or more mitotic figures per 10 high power fields. We have experienced a rare case of malignant ovarian fibrothecoma in a 72-year-old postmenopausal woman. We report a case with brief review of literature.

Keyword

Thecoma; Fibroma; Malignant neoplasms; Ovary; Mitotic Index

MeSH Terms

Aged
Female
Fibroma
Humans
Mitotic Index
Ovary
Thecoma

Figure

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  Fig. 1 Well defined heterogenous echoic solid mass (11.3×11.7×10.2 cm) with some tiny cystic changes abuting on atrophic uterus in right adnexa.

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  Fig. 2 The specimen received for frozen section consists of a circumscribed ovarian mass (16×16 cm), which is composed of yellow-gray solid firm mass with focal myxoid change.

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  Fig. 3 The tumor is composed of cellular, oval to spindle cells with pale cytoplasm and frequent mitosis (arrows) (H&E,×400).

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  Fig. 4 The tumor cells are positive for vimentin (A) and alpha-inhibin (B). (Immunohistochemistry,×400).

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